Follow this step-by-step protocol to suppress cellular aging inflammation using apigenin, spermidine, and NAD support.
Based on: They Screened 66 Compounds for Anti-Aging - This One Won (and it's in parsley) by Thomas DeLauer
What if the most powerful anti-aging compound scientists could find wasn't a drug, wasn't an expensive biohack — it was sitting in the garnish on your dinner plate? That's exactly what a 2025 study published in Advanced Science discovered when researchers screened 66 natural compounds for longevity activity. One won by a landslide. And Thomas DeLauer breaks down exactly why it matters — and more importantly, what to do about it.
Here's the frustrating reality most people face: you're probably already thinking about aging. Maybe it's the gray hairs showing up earlier than expected, the slower recovery after workouts, the low energy that doesn't respond to coffee the way it used to. You do your research, you try supplements, but nobody hands you a clear, organized protocol that tells you what to take, when to take it, and why it works together. You end up with a shelf full of half-used bottles and no real system.
Imagine instead waking up with a precise, science-backed daily routine. You know exactly when to take apigenin with your fat-containing meal for maximum absorption. You know to pair it with your existing NMN or NR stack because apigenin actually blocks the enzyme that degrades your NAD — something most people completely miss. You take spermidine in your fasted window to activate mitophagy, the cellular recycling process that keeps your mitochondria strong. Your protocol isn't random. It's targeted. It addresses senescent cell inflammation, NAD degradation, and mitochondrial damage — the three key drivers Thomas identifies as central to the aging equation.
Thomas DeLauer has built one of the most trusted science-forward health channels on YouTube, known for translating dense peer-reviewed research into practical, actionable guidance. This video pulls from studies in Geroscience, Advanced Science, Diabetes, Scientific Reports, and Nature Cell Biology. When he says the mechanistic data is strong and the risk profile is low, that's not hype — that's a researcher who has done the reading.
This checklist captures every specific action, dose, timing detail, and pairing strategy from the video in one clean, printable PDF. No more rewinding the video to catch a dosage. No more guessing whether to take something with food or fasted. Every step is laid out in order, with the context you need to actually follow through.
If you're serious about longevity and you want a protocol grounded in real research — not trends — this checklist is your starting point. Download it, print it, and start building your stack today.
Every checklist item comes with actionable notes to guide you — things like "Don't forget to do this before you start," "Avoid this common mistake," or "Set a reminder for 30 days out." Nothing vague, just clear next steps.
+ 15 more action items inside...
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